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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5907c058f83d8aa556fdf2e803b83eedc2ddacea9f0e75b3c53750404574cee8' 
  AND token = '7h4k33OhSzep1UEzetRo9X6bnbmfvU9bpBtrdljubPA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}