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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b720860a66bb9efe98856d9a8bbac389e11b5a161c94fb110c142c41b15bee35' 
  AND token = 'GZOFrzyAUMvNiUUySISAp9XvbwH4RK9sT19E6tbXakw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00011

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}