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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e9af8d2c706bdc84a3fd2273602e7227631199c1b54bb1b98d3ba57af2e8254' 
  AND token = 'TcY5gu3lCTUuh+0wRwRv2RDOXpHLOFMCUvyUyyp8spA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00011

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}